scienceofprevention Day 1
https://scienceofprevention.com/alz/alzheimers-epidemic/?inf_contact_key=a05806dedff6b0b98f5eae1a0795d96d09c74070ac2bf3cfa7869e3cfd4ff832
Host: David Perlmutter, MD, Board-Certified Neurologist & #1 NYT Bestselling AuthorEPISODE 1
OCTOBER 9: THE ALZHEIMER’S EPIDEMIC
In this episode, we will cover the essential background of this devastating disease. We’ll discuss the following topics, and so much more.
- What Alzheimer’s is, and what is happening in the brain
-The one thing that is at the root of Alzheimer’s disease and all chronic degenerative diseases
-Why Alzheimer’s has reached epidemic proportions
-What makes a good brain go bad
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alz is a disease for which there is no meaningful treatment
5.5mil people currently diagnosed w/alz in America, 40mill in world, new case every 3 seconds
The science of prevention...
at 85yrs old, risk is 50/50
dementia: cognitivek capacity, visual, spacial, attention, memory is affected to the extent you cannot perform daily activities
alz: a subtype of dementia, cannot take care of themselves
alz is not a disease, rather, a catastrophic end stage of a progression of change that is probably in most individuals preventable
why alz incidence is increasing
- we are an aging society
- environmantal changes
- - driving inflamation, & present in all alz patients' brains
- - main brain damage cause: inflamation
- - must deal w/cause of inflamation
- - inflamation can prodduce feelings of depression, anxiety
- - - infl. in mid-life is related to reduced brain volume later in life
- - - closely tethered to alz, dementia, heart disease, type2 diabedies & obesity
- how alz starts;
- - 1st, person develops insulin resistance whether pre-diabedies or diabedies which starts the inflamatory cascade
- - - that leads to increased inflamation in the brain to the point at which the system of reserve in the brain is overwhelmed
- - - - that leads to connections' damage
- - - 1st area affected is focus and short term memory in the hypocampus and cascade goes from there to the greater brain and alz
- need to have a multi-pronged prevention plan
- - insulin resistance & diabedies, wrong foods
- - poor sleep
- - lack of exercise
- brain changes begin 20 to 30 years before alz is diagnosed
- need corret food, sleep
- don't wait until suffering from memory loss to change what you are doing
- - pre-natal(what mom eats affects baby), what children eat (breast feeding or not), toxin exposure, biomarkers related to alz,
      blood sugar and insulin, levels of B vitamines, gut, toxic load, level of exercise, sleep, stress, developing belly fat
- - IF YOU HAVE BELLY FAT THEN YOU HAVE BRAIN DAMAGE!!!
- preventive measures are really effective; 5 most important points
- - 1: diet; get yourself into mild ketosis, have an anti-inflamatory diet to imporve you insulin sensitivity & optoise your micro-biome
      and appropriate times of fasting
- - 2: exercise, both strength training and aerobic exercise
- - 3: sleep, 7-8hrs of restorative sleep
- - 4: reduce stress (seek joy, meditate)
- - 5: brain training a few times a week (learn new language, chalenge your brain)
- - beyond that... hormone balancing, specific herbs and nutrients
- changes most needed to avoid alz
- - avoid processed foods, carbohydrates, vegetable oils
- - - that stuff leads to insulin resistance... then to chronic inflamation... then type-2 dibedies & type-3 diabedies
- trinity of healath, non-negotiable things:
- - optmise sleep
- - optomise nutrition w/low carbohydrates
- - exercise
- how preventable?
- - look at genetics
- - 95% could be prevented
- - 5% where genetics have high penetrance
- - 99% of risk is in your own hands by what you do...
- your brain is you

KF!